The use of liquid chromatography with on-line fluorescence detection has formed the basis for the separation, characterisation and quantitation of a number of metabolites of the psychotomimetic indolealkylamines N,N-dimethyltryptamine and 5-methoxy-N,N-dimethyltryptamine formed both in vitro and in vivo. Verification of the identity of metabolites has previously been facilitated by the combined...
A rapid, sensitive and specific method for the screening of hallucinogenic mushrooms has been developed. High-performance liquid chromatography with simultaneous use of ultraviolet, fluorescence and electrochemical detection was employed. Separation of the mushroom components was achieved on a silica column using an alkaline aqueous methanolic eluent. The use of detector response ratios for...