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Journal of advanced pharmacy education and research

ISSN 2249-3379

1 paper in the library · publishing 2025

Papers

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The potential therapeutic effect of donepezil on a ketamine rat model of psychosis ‎

Journal of advanced pharmacy education and research 2025 K. Mehdar

Mental illnesses like bipolar disorder and schizophrenia often present psychotic symptoms. Current antipsychotic medications, including clozapine, can cause serious side effects. This study investigates the potential therapeutic effects of the cholinesterase inhibitor donepezil compared to clozapine in a ketamine-induced psychosis model in rats. Forty adult male albino rats were divided into...