PSYCHEDELICS AND ENTACTOGENS IN PSYCHIATRY: PHARMACOLOGY, CLINICAL TRIAL EVIDENCE, AND REGULATORY CONSIDERATIONS
Global Journal of Research in Biology and Pharmacy October 31, 2025 Ifeyinwa Adar Opoku
Psychedelics, including psilocybin, lysergic acid diethylamide, and dimethyltryptamine, and entactogens such as 3,4-methylenedioxymethamphetamine are being investigated for treatment-resistant depression, post-traumatic stress disorder, anxiety, and substance use disorders. These compounds act primarily through serotonin 5-HT2A receptor agonism (psychedelics) or monoamine release (MDMA),...