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McMaster University Medical Journal

ISSN 1927-2421

2 papers in the library · publishing 2025-2026

Papers

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Intravenous Ketamine for Depression and Suicidality in Borderline Personality Disorder and Borderline Personality Features: A Systematic Review

McMaster University Medical Journal July 26, 2026 Annie Xiong, Sebastian Kolde, Paul Links

Background: Pharmacologic treatment options for borderline personality disorder (BPD) remain limited, and no medication has received regulatory approval for its treatment. Given the high rates of comorbid depression and suicidal ideation in BPD, there is growing interest in novel therapeutic approaches. Ketamine has been approved for treatment-resistant depression and acute suicidality, raising...

Mindfulness-Based Cognitive Therapy History and Mechanisms

McMaster University Medical Journal March 25, 2025 Madeline Komar, Jordan Pepper, Irene Zhao et al.

Mindfulness has become a popular term in the 21st-century zeitgeist. Researchers have attempted to establish that anyone can reap benefits from practicing mindfulness, ranging from healthcare professionals (HCPs) and business executives to patients experiencing florid psychosis. Given the abundance of research on mindfulness-based intervention, it would be prudent for HCPs to understand the...