Review of Ketamine as a Rapid Antidepressant for Treatment-Resistant Depression
Scholarly Research In Progress November 8, 2021 Sankung X. Darboe, Peter J. Koszuta, Paul W. Lee et al.
The anesthetic agent ketamine has been under investigation as a potential antidepressant for two decades. Animal studies and subsequent randomized control trials for patients have provided extensive evidence of ketamine’s rapid antidepressant outcomes both structurally at the receptor level as well as behaviorally. A review of current literature hones in on the putative rapid mechanisms of...