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Journal of Clinical Medicine

ISSN 2077-0383

53 papers in the library · 279 citations · publishing 2016-2026

Papers

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Evaluation of a Modified Mindfulness-Based Stress Reduction Intervention for Adults with Cerebral Palsy and Anxiety and/or Emotion Regulation Difficulties-A Randomised Control Trial.

Journal of Clinical Medicine December 19, 2023 Hayley Smithers-Sheedy, Emma Waight, Katherine L Swinburn et al. 4 citations

Mindfulness-Based Stress Reduction (MBSR) has not yet been evaluated for people with cerebral palsy (CP). The aims of this randomised control trial were to investigate whether a modified telehealth MBSR program could improve mindfulness and reduce depression, anxiety, and emotion regulation difficulties among adults with CP with elevated anxiety and/or emotional regulation difficulties....

DOI: 10.3390/jcm13010001 (opens in new tab) Full text (opens in new tab) Anxiety Cerebral palsy Emotion regulation Mindfulness-based stress reduction

Effects of an App-Based Mindfulness Intervention during Pregnancy on the Infant’s Prenatal Androgen Exposure: A Randomized Controlled Pilot Trial

Journal of Clinical Medicine September 23, 2023 Eva-Maria Siegmann, Anna Eichler, Verena Nadine Buchholz et al. 2 citations

Prenatal androgen exposure modulates the development of the brain, with lasting effects on its function and behavior over the infant’s life span. Environmental factors during pregnancy, in particular maternal stress, have been shown to influence the androgen load of the unborn child. We here addressed the research gap on whether a mindfulness intervention or a pregnancy education administered...

Comparing the Effectiveness of Mindfulness-Based Stress Reduction with Acceptance and Commitment Therapy on Social Anxiety and Its Dimensions in Stuttering Adults

Journal of Clinical Medicine August 9, 2023 Alireza Salehpoor, Zahra Yousefi, Mohsen Golparvar

Background and Objective: Adults with stuttering show a fear of communication. This study aimed to compare the effectiveness of mindfulness-based stress reduction to that of acceptance and commitment therapy on social anxiety and its dimensions in adults with stuttering. Materials and Methods: This study was a semi-experimental type with a pretest-posttest and follow-up design. The statistical...

Awake or Sleeping? Maybe Both… A Review of Sleep-Related Dissociative States.

Journal of Clinical Medicine June 6, 2023 Maria Eduarda Sodré, Isabel Wießner, Muna Irfan et al. 15 citations

Recent studies have begun to understand sleep not only as a whole-brain process but also as a complex local phenomenon controlled by specific neurotransmitters that act in different neural networks, which is called "local sleep". Moreover, the basic states of human consciousness-wakefulness, sleep onset (N1), light sleep (N2), deep sleep (N3), and rapid eye movement (REM) sleep-can concurrently...

How Does Meditation-Based Lifestyle Modification Affect Pain Intensity, Pain Self-Efficacy, and Quality of Life in Chronic Pain Patients? An Experimental Single-Case Study.

Journal of Clinical Medicine May 31, 2023 Karin Matko, Meike Burzynski, Maximilian Pilhatsch et al. 5 citations

Chronic pain is a growing worldwide health problem and complementary and integrative therapy options are becoming increasingly important. Multi-component yoga interventions represent such an integrative therapy approach with a promising body of evidence. The present study employed an experimental single-case multiple-baseline design. It investigated the effects of an 8-week yoga-based mind-body...

Sleep Paralysis and Lucid Dreaming-Between Waking and Dreaming: A Review about Two Extraordinary States.

Journal of Clinical Medicine May 12, 2023 Severin Ableidinger, Brigitte Holzinger 13 citations

Sleep paralysis and lucid dreams are two states of consciousness that are connected to REM sleep but are defined by higher awareness in contrast to regular REM sleep. Despite these similarities, the two states differ widely in their emotional tone and their perceived controllability. This review aims to summarize the current research containing sleep paralysis and lucid dreams. However, given...

App-Based Mindfulness Meditation Training and an Audiobook Intervention Reduce Symptom Severity but Do Not Modify Backward Inhibition in Adolescent Obsessive-Compulsive Disorder: Evidence from an EEG Study

Journal of Clinical Medicine March 24, 2023 Sarah Rempel, Lea L. Backhausen, Maria McDonald et al.

(1) Background: 1–2% of children and adolescents are affected by Obsessive-Compulsive Disorder (OCD). The rigid, repetitive features of OCD and an assumed disability to inhibit recent mental representations are assumed to have led to a paradoxical advantage in that the Backward Inhibition (BI) effect was recently found to be lower in adolescents with OCD as compared to healthy controls. It was...

Lapses of the Heart: Frequency and Subjective Salience of Impressions Reported by Patients after Cardiac Arrest.

Journal of Clinical Medicine March 2, 2023 Fritz Sterz, Michael L Berger, Gerhard Ruzicka et al.

After cardiac arrest (CA), some patients report impressions with highly realistic features, often referred to as near-death experience (NDE). The frequency of such episodes seems to be variable, with various types of content. In a prospective study, we subjected 126 CA cases treated at the Department of Emergency Medicine of the Medical University of Vienna under carefully controlled conditions...

DOI: 10.3390/jcm12051968 (opens in new tab) Full text (opens in new tab) Cardiac arrest Cardiopulmonary resuscitation Meeting deceased relatives Structured interview +2

Intraoperative Low-Dose S-Ketamine Reduces Depressive Symptoms in Patients with Crohn’s Disease Undergoing Bowel Resection: A Randomized Controlled Trial

Journal of Clinical Medicine February 1, 2023 Zhen Zhang, Wen-Hao Zhang, Yin Lu et al.

Background: Patients with Crohn’s disease (CD) undergoing bowel resection often suffer from depression and acute pain, which severely impairs their recovery. We aimed to investigate the effects of S-ketamine preconditioning on postoperative depression in patients with CD undergoing a bowel resection with mild to moderate depression and to observe whether it can relieve postoperative pain and...

Meditation and Irritable Bowel Syndrome, a Systematic Review and Meta-Analysis.

Journal of Clinical Medicine November 2, 2022 Cristian-Ioan Baboș, Daniel-Corneliu Leucuța, Dan Lucian Dumitrașcu

Mind-body interventions have shown efficacy in many conditions that have psychosomatic mechanisms, as well as for other pathologies. The aim of this study was to assess the effectiveness of meditation/mindfulness at improving the symptoms severity, quality of life and other associated mood and mental conditions, measured in patients with irritable bowel syndrome (IBS). A systematic review of...

Dreaming in Parasomnias: REM Sleep Behavior Disorder as a Model.

Journal of Clinical Medicine October 28, 2022 Elisabetta Fasiello, Serena Scarpelli, Maurizio Gorgoni et al.

Sleep parasomnias have drawn the interest of sleep experts because they represent a valuable window to directly monitor dream activity and sleep mentation associated with nocturnal events. Indeed, parasomnias and their manifestations are helpful in investigating dream activity and features, overcoming methodological limits that affect dream study. Specifically, REM sleep Behavior Disorder (RBD)...

DOI: 10.3390/jcm11216379 (opens in new tab) Full text (opens in new tab) Dream contents Dream recall frequency Oneiric activity Parasomnias

Effects of Meditation on Cardiovascular and Muscular Responses in Patients during Cardiac Rehabilitation: A Randomized Pilot Study.

Journal of Clinical Medicine October 18, 2022 Maximilian E Rudlof, Boštjan Šimunić, Bianca Steuber et al.

Cardiovascular diseases are the world's number one cause of death, with exceeding psychosocial stress load being considered a major risk factor. A stress management technique that has repeatedly shown positive effects on the cardiovascular system is the Transcendental Meditation (TM) technique. The present pilot study aimed to investigate the potential effect of TM on the recovery of cardiac...

DOI: 10.3390/jcm11206143 (opens in new tab) Full text (opens in new tab) Cardiac rehabilitation Cardiovascular diseases Psychosocial stress Tensiomyography +1

Stress Reduction by Yoga versus Mindfulness Training in Adults Suffering from Distress: A Three-Armed Randomized Controlled Trial including Qualitative Interviews (RELAX Study).

Journal of Clinical Medicine September 26, 2022 Jan Moritz Fischer, Farid-Ihab Kandil, Christian S Kessler et al.

Distress is a growing public health concern. In this three-armed randomized controlled trial, n = 102 adults with elevated stress levels and stress-related symptoms were randomly assigned to (1) “integrative” yoga classes which combined physical exercises, mindfulness training, and ethical/philosophical aspects of traditional yoga; to (2) Iyengar yoga classes which entailed primarily physical...

Who Benefits Most? Interactions between Personality Traits and Outcomes of Four Incremental Meditation and Yoga Treatments.

Journal of Clinical Medicine August 4, 2022 Karin Matko, Anne Berghöfer, Michael Jeitler et al.

Mind-Body Medicine (MBM) includes a broad range of interventions with proven preventive and clinical value, such as yoga and meditation. However, people differ in their preferences and response to different MBM treatments and it remains unclear who benefits most from what type of practice. Thus, finding moderators of treatment outcome seems to be a promising approach. This was the aim of the...

DOI: 10.3390/jcm11154553 (opens in new tab) Full text (opens in new tab) Meditation Cluster analysis Mind–body medicine Moderators +2

MDMA for the Treatment of Negative Symptoms in Schizophrenia

Journal of Clinical Medicine June 7, 2022 Mitchell Arnovitz, Andrew Spitzberg, Ashkhan J. Davani et al. 29 citations

The profound economic burden of schizophrenia is due, in part, to the negative symptoms of the disease, which can severely limit daily functioning. There is much debate in the field regarding their measurement and classification and there are no FDA-approved treatments for negative symptoms despite an abundance of research. 3,4-Methylenedioxy methamphetamine (MDMA) is a schedule I substance...

DOI: 10.3390/jcm11123255 (opens in new tab) MDMA Schizophrenia object-oriented programming Methamphetamine

Effect of Mindfulness-Based Stress Reduction on the Well-Being, Burnout and Stress of Italian Healthcare Professionals during the COVID-19 Pandemic

Journal of Clinical Medicine May 31, 2022 Marco Marotta, F. Gorini, Alessandra Parlanti et al.

COVID-19 has overwhelmed healthcare systems and increased workload and distress in healthcare professionals (HCPs). The objective of this study was to evaluate baseline distress before and after the pandemic, and the effect of Mindfulness-Based Stress Reduction (MBSR) training on well-being (PGWBI), stress (PSS) and burnout (MBI) in Italian HCPs. Moreover, the “fear of COVID-19” (FCV-19S)...

Ayahuasca as a Decoction Applied to Human: Analytical Methods, Pharmacology and Potential Toxic Effects

Journal of Clinical Medicine February 21, 2022 Ľuboš Nižňanský, Žofia Nižnanská, Roman Kuruc et al. 11 citations

Ahyahuasca is a term commonly used to describe a decoction prepared by cooking the bark or crushed stems of the liana Banisteriopsis caapi (contains β-carbolines) alone or in combination with other plants, most commonly leaves of the shrub Psychotria viridis (contains N,N-dimethyltryptamine-DMT). More than 100 different plants can serve as sources of β-carbolines and DMT, which are the active...

DOI: 10.3390/jcm11041147 (opens in new tab) Ayahuasca Decoction Liana Traditional medicine +4

Abuse Potential of Cathinones in Humans: A Systematic Review

Journal of Clinical Medicine February 15, 2022 Lourdes Poyatos, A Acuna Torres, Esther Papaseit et al. 26 citations

Introduction and objective: Assessing the abuse potential of new substances with central nervous system activity is essential for preventing possible risks of misuse and addiction. The same methodology is recommended for the evaluation of the abuse potential of recreational drugs. This systematic review aims to assess the pharmacological effects related to the abuse potential and...

Trajectory of Antidepressant Effects after Single- or Two-Dose Administration of Psilocybin: A Systematic Review and Multivariate Meta-Analysis

Journal of Clinical Medicine February 11, 2022 Chia‐ling Yu, Chih-Sung Liang, Fu-Chi Yang et al. 37 citations

We examined the cardiovascular safety, acceptability, and trajectory of the antidepressant effects of psilocybin after single- or two-dose administration. Four major electronic databases were systematically searched. Data were pooled using a multivariate random-effects meta-analysis. Primary outcomes were changes in depressive symptoms. Secondary outcomes were cardiovascular safety and...

DOI: 10.3390/jcm11040938 (opens in new tab) Psilocybin Placebo Meta-analysis Discontinuation +5

Mindfulness-Based Program for Anxiety and Depression Treatment in Healthcare Professionals: A Pilot Randomized Controlled Trial.

Journal of Clinical Medicine December 17, 2021 Mirian Santamaría-Peláez, Jerónimo Javier González-Bernal, Juan Carlos Verdes-Montenegro-Atalaya et al.

In primary health care, the work environment can cause high levels of anxiety and depression, triggering relevant expert and individual change. Mindfulness-Based Stress Reduction (MBSR) programs reduce signs of anxiety and depression. The purpose of this sub-analysis of the total project, was to equate the effectiveness of the standard MBSR curriculum with the abbreviated version in minimizing...

Psychological Therapy in Chronic Pain: Differential Efficacy between Mindfulness-Based Cognitive Therapy and Cognitive Behavioral Therapy

Journal of Clinical Medicine August 1, 2021 E. M. Pardos-Gascón, Lucas Narambuena, César Leal-Costa et al.

The objective of this study is to evaluate the differential efficacy between Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behavioral Therapy (CBT). A quasi-experimental design of repeated measures before and after the test (n = 57) was used with a non-equivalent control group from a previous cohort treated with CBT (n = 105). The t-test revealed significant differences in subjective...

Nightmares in Patients with Major Depressive Disorder, Bipolar Disorder, and Psychotic Disorders: A Systematic Review.

Journal of Clinical Medicine December 9, 2020 Marine Ambar Akkaoui, Michel Lejoyeux, Marie-Pia d'Ortho et al.

Chronic nightmares are very common in psychiatric disorders, affecting up to 70% of patients with personality or post-traumatic stress disorders. In other psychiatric disorders, the relationships with nightmares are poorly known. This review aimed to clarify the relationship between nightmares and both mood and psychotic disorders. We performed a systematic literature search using the PubMed,...

Yoga and Mindfulness as a Tool for Influencing Affectivity, Anxiety, Mental Health, and Stress among Healthcare Workers: Results of a Single-Arm Clinical Trial

Journal of Clinical Medicine April 1, 2020 G. L. Torre, Antonino Raffone, Margherita Peruzzo et al.

Mindfulness-based interventions have emerged as unique approaches for addressing a range of clinical and subclinical difficulties such as stress, chronic pain, anxiety, or recurrent depression. Moreover, there is strong evidence about the positive effects of yoga practice on stress management and prevention of burnout among healthcare workers. The aim of this study was to conduct a single-arm...

Effects of Meditative Movements on Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal of Clinical Medicine August 1, 2018 Liye Zou, Albert Yeung, Chunxiao Li et al.

Tai Chi, Qigong, and Yoga are recognized as the most popular complementary approaches for alleviating musculoskeletal pain, improving sleep quality, and reducing blood pressure. The therapeutic effects of these meditative movements for treating major depressive disorder (MDD) is yet to be determined. Therefore, we examined whether meditative movements (Tai Chi, Qigong, and Yoga) are effective...

DOI: 10.3390/jcm7080195 (opens in new tab) Full text (opens in new tab) Depression Exercise Mindfulness/meditation Mood disorders +1