The abuse of new psychoactive substances is severe globally. Among phenethylamine compounds, mescaline and its analogues are a class of substances that are often overlooked, yet their abuse has shown a gradual increase in recent years. This paper reviews mescaline and its analogues from three aspects: their basic information, pharmacological and toxicological properties, and detection methods....
Fa yi xue za zhiApril 25, 2025Yu-Meng Zuo, Wei Han, Jian-Bo Zhang et al.
Ketamine is a dissociative anesthetic. It is clinically used as a surgical anesthetic or anesthetic inducer and has a certain degree of mental dependence. Its abuse can lead to nerve damage, adverse emotional reactions and other toxic side effects. The primary mechanism by which ketamine exerts its pharmacological effects is to block N-methyl-D-aspartate receptors (NMDAR). It also functions...