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Clinical Research and Clinical Trials

ISSN 2693-4779

2 papers in the library · publishing 2021-2025

Papers

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Phase 0 Experimental Medicine Study of Direct Intratarget Pulmonary Microdosing of nlrp3/1 Inflammasome Inhibitor ads032: the Micro Study. A Protocol Paper

Clinical Research and Clinical Trials November 18, 2025 Tom M. Quinn, A Bruce, S Dickson et al.

Introduction High attrition in drug development remains a significant challenge for research and development organisations worldwide. Most novel drug compounds fail at an early stage, often without knowledge of target engagement or molecular efficacy at diseased tissue level. Phase 0 trials provide an opportunity to provide mechanistic data in a small number of patients at the earliest stage of...

The Effects of Neurosculpting® Meditation on Stress, Anxiety and Sleep on one group of college students

Clinical Research and Clinical Trials September 29, 2021 Kathleen Kelley

Objective: The purpose of this study was to examine if 11 weeks of Neurosculpting® meditation improved sleep and other variables in college aged students. Participants: Fifteen undergraduate students. Methods: Subjects were evaluated at the beginning and end of the semester using two tools: The Pittsburg Sleep Quality Index and the Depression Anxiety Stress Scale. During each session, heart...