Psychiatriki
February 19, 2026
Orestis Giotakos
The concept of timing is an interesting way to understand how the body and brain construct the concept of self, but also how self-distortions arise in the case of psychosis. Analysis of temporal representations in psychosis highlights a deficit that includes both the subjective experience of the flow of time, i.e., time perception, and the ability to process temporal information inherent to any...
Psychiatriki
July 2, 2025
Dimitrios Sakellion, Shokhrukh Sultanov, Dilmurad Irgashev et al.
Hypnosis is an externally induced alteration in consciousness as a result of suggestion. Hypnotherapy, also called clinical hypnosis, is the use of hypnosis as psychological treatment, either brief or long-term psychotherapy, for alleviating pain, inducing habit modification, and treating a range of physical and mental health problems, such as psychosomatic diseases, mood and anxiety disorders,...
Psychiatriki
October 8, 2024
Petros Fotiadis, Eleni Tsalkitzi, Dimos Dimellis et al.
Esketamine is a non-selective, competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor in the brain. Through NMDA receptor antagonism, esketamine causes a transient increase in glutamate release, leading to increases in neurotrophic signaling and restoration of synaptic function in brain regions involved in mood regulation and emotional behavior. Several randomized clinical trials...
Psychiatriki
October 12, 2023
Orestis Giotakos
1 citation
In philosophy, intentionality involves directedness, aboutness, or reference of mental states. It seems to have intense connections with mental representation, consciousness, as well as evolutionary selected functions. Naturalizing intentionality, in terms of tracking or functional roles, is one of the most important goals in philosophy of mind. Such what-matters models would be useful,...
Psychiatriki
December 20, 2021
Τheodosios Ε Christodoulakis
1 citation
Τhe Food and Drug Administration (FDA) approval of the use of S-ketamine in the form of nasal spray for the treatment of treatment-resistant depression, launched a new category of therapeutic agents in psychiatry. A well-known class of substances, psychedelics, are introduced with a 30-year delay in the treatment of mental disorders. Intravenous ketamine infusion has been studied in the...
Psychiatriki
December 20, 2021
Styliani Kaliora
1 citation
Despite major advances in the treatment of mood disorders, major depression, a common mental disorder, remains a serious public health problem. Electroconvulsive therapy (ECT) regardless of the anesthetic agent used, is the most effective form of treatment in major depression and the gold standard therapy in treatment resistant depression. Ketamine is one of the anesthetic drugs approved by the...
Psychiatriki
December 20, 2021
Grigorios N. Karakatsoulis, Eva-Maria Tsapakis, Konstantinos Ν. Fountoulakis
1 citation
Treatment-Resistant Depression (TRD) calls for the development of effective interventions for mood elevation and stabilization. Recently, both ketamine and its S-enantiomer (esketamine) have been investigated with successful clinical trials demonstrating effectiveness in TRD. More specifically, in 2019, intranasally administered esketamine, as opposed to the more effective intravenous ketamine,...
Psychiatriki
2019
K Laios, P Lytsikas-Sarlis, K Manes et al.
Drugs with psychedelic, hypnotic, narcotic, analgesic, suppressive, euphoric and stimulating effects were used in various ways during the ancient times. We can classify drug use in ancient times into two main categories. On the one hand, ancient physicians prescribed drugs based on their pharmaceutical-therapeutic actions. On the other hand, people not pertaining to medicine and not relating to...
Psychiatriki
2017
O Giotakos
A variety of phenomena might be considered as reflecting impaired insight in psychosis, like failure to recognize signs, symptoms or disease, failure to derive appropriate cognitive representations, despite recognition of the disease, and misattribution of the source or cause of the disease. The unawareness of tardive dyskinesia symptoms in schizophrenic patients points that self-awareness...