Ketamine Reverses Depressive-Like Behavior Induced by Optogenetic Stimulation of Glutamatergic Neurons in the Dorsal Hippocampus
Нейрохимия / Neurochemical Journal 2025 U. S. Drozd
The hippocampus is one of the brain structures whose functions and morphology are impaired in depression. The fast-acting antidepressant ketamine reverses these impairments, but the mechanisms of its action are still not fully understood. Optogenetic stimulation of glutamatergic neurons in the CA1 region of the dorsal hippocampus of rats with the preliminary introduction of vectors expressing...