Treatment-resistant depression (TRD) is one of the most debilitating conditions that does not respond to conventional pharmacotherapy. Ketamine is a recently used effective treatment option in depressive disorders with a novel mechanism of action. Still, studies estimating the improvement of depressive symptoms in TRD with multiple doses of ketamine are limited. Hence, we report 5 TRD cases...
This brief clinical review summarizes the literature on sleep paralysis most relevant to clinicians. Sleep paralysis is a condition where the sufferer awakens to rapid eye movement sleep based atonia, combined with conscious awareness. This is a frightening event accompanied by vivid, waking dreams and hallucinations. Sleep paralysis occurring independent of narcolepsy and other medical...