Evaluation of SK-N-SH Cells as a Model for NMDA Receptor Induced Toxicity.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology August 30, 2024 Gunnar Goerges, Paul Disse, Stefan Peischard et al. 2 citations
Over the years, the number of patients with neurodegenerative diseases is constantly rising illustrating the need for new neuroprotective drugs. A promising treatment approach is the reduction of excitotoxicity induced by rising (S)-glutamate levels and subsequent NMDA receptor overactivation. To facilitate the search for new NMDA receptor inhibitors neuronal cell models are needed. In this...
DOI: 10.33594/000000722 (opens in new tab)
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Neurotoxicity neurotoxic effects
Neural toxicity
Nerve cell damage
Alzheimer disease
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