Age-related alterations in default mode network: Impact on working memory performance
Neurobiology of Aging August 1, 2008 Fabio Sambataro, Vishnu P. Murty, Joseph H. Callicott et al. 534 citations
The default mode network (DMN) is a set of functionally connected brain regions which shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows an age-related decline in task-load-related modulation of the activity within the DMN during cognitive tasks. However, the effect of age on the functional coupling within the DMN and their relation to cognitive...