The molecular basis of the antidepressant action of the magic mushroom extract, psilocin.
Biochimica et biophysica acta. Proteins and proteomics July 1, 2023 Ali Asghar Hakami Zanjani, Teresa Quynh Tram Nguyen, Luise Jacobsen et al. 6 citations
Magic mushrooms, and their extract psilocybin, are well-known for their psychedelic properties and recreational use. Psilocin, the bio-active form of psilocybin, can potentially treat various psychiatric diseases. Psilocin putatively exerts its psychedelic effect as an agonist to the serotonin 2A receptor (5-HT2AR), which is also the receptor for the neurological hormone serotonin. The two key...