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Teresa Quynh Tram Nguyen

2 papers in the library · 15 citations · publishing 2022-2023

Papers

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The molecular basis of the antidepressant action of the magic mushroom extract, psilocin.

Biochimica et biophysica acta. Proteins and proteomics July 1, 2023 Ali Asghar Hakami Zanjani, Teresa Quynh Tram Nguyen, Luise Jacobsen et al. 6 citations

Magic mushrooms, and their extract psilocybin, are well-known for their psychedelic properties and recreational use. Psilocin, the bio-active form of psilocybin, can potentially treat various psychiatric diseases. Psilocin putatively exerts its psychedelic effect as an agonist to the serotonin 2A receptor (5-HT2AR), which is also the receptor for the neurological hormone serotonin. The two key...

Magic mushroom extracts in lipid membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes May 10, 2022 Teresa Quynh Tram Nguyen, Frederik W. Lund, Ali Asghar Hakami Zanjani et al. 9 citations

The active hallucinogen of magic mushrooms, psilocin, is being repurposed to treat nicotine addiction and treatment-resistant depression. Psilocin belongs to the tryptamine class of psychedelic compounds which include the hormone serotonin. It is believed that psilocin exerts its effect by binding to the serotonin 5-HT2A receptor. However, recent in-vivo evidence suggests that psilocin may...