A Systematic Review of Study Design and Placebo Controls in Psychedelic Research.
Psychedelic Medicine March 12, 2024 Alexander Wen, Nikhita Singhal, Brett D. M. Jones et al. 36 citations
Introduction: Effective blinding is especially challenging in randomized controlled trials (RCTs) involving psychedelics due to the inherent alterations in consciousness that these compounds induce. In this systematic review and exploratory analysis, we aim at synthesizing the methodologies used in RCTs involving classic psychedelics and identify procedures that can help minimize unblinding and...
DOI: 10.1089/psymed.2023.0028 (opens in new tab)
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Psychedelic medicine
Clinical research methodology
Placebo controls
Mental health treatments
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