Systematic review of clinical effectiveness of interventions for treatment resistant late-life depression.
Ageing Research Reviews May 1, 2025 Beatriz Pozuelo Moyano, Denise Gomez Bautista, Karla Jocelyn Porras Ibarra et al. 12 citations
Treatment-resistant late-life depression (TRLLD) affects nearly half of older adults with major depression. This systematic review evaluates published evidence of effectiveness of both pharmacological and non-pharmacological treatments for TRLLD. A search of MEDLINE, EMBASE, CINAHL, PsycINFO, the Cochrane Library, and online trial registries up to March 2024 was conducted to identify randomized...
DOI: 10.1016/j.arr.2025.102710 (opens in new tab)
Full text (opens in new tab)
Treatment-resistant depression
Late life depression
Older people
Randomized controlled trials
+4