BackgroundWhile psychedelic treatments for difficult-to-treat mental health conditions are advancing, participant perspectives remain under-explored. This study examined former participants’ experiences across recruitment, preparation, dosing, integration and study ending, and generated recommendations for future trials and treatment delivery.MethodsThis qualitative descriptive study, informed...
As psychedelic treatments approach licensing with reduced clinical intensity, the psychological functions previously served by integration support are increasingly displaced onto patients' social environments. This Perspective argues that these environments are plausible but unmeasured moderators of outcome, and proposes three responses: structured psychoeducation for support networks,...
Psychedelic substances exhibit complex interactions with the 'set and setting' of use, that is, the mental state of the user and the environment in which a psychedelic experience takes place. Despite these contextual variables' known importance, psychedelic research has lacked methodological rigor in reporting extra-pharmacological factors. This study aimed to generate consensus-based...