Classic psychedelics, including psilocybin, LSD, DMT, 5-MeO-DMT, mescaline, and phenethylamines such as DOI, exert their core effects through 5-HT2A receptor agonism, inducing widespread neurobiological and behavioral changes relevant to psychiatric research. Emerging evidence suggests that these effects are modulated by sex, yet this dimension remains underrepresented in studies. This review...
This review explores an innovative, integrative therapeutic approach that combines probiotics, prebiotics, and mindfulness-based interventions (MBIs) to target the dysregulation of the gut–brain axis in schizophrenia. The rationale for this combined strategy is rooted in the overlapping mechanisms by which both biological and psychosocial interventions influence neurophysiological processes....