T. U. C. Järbe

Characteristics of tetrahydrocannabinol (THC)-produced discrimination in rats

Psychopharmacology 1976 T. U. C. Järbe, J. O. Johansson, B. G. Henriksson 40 citations

Rats were trained in a T-shaped maze to discriminate the effects produced by i.p. injections of tetrahydrocannabinol (THC) and the no-drug state (state-dependency, StD). Several doses of both Δ^8-THC (range: 0.75–5.0 mg/kg) and Δ^9-THC (range: 0.75–10.0 mg/kg) were used in order to compare the number of sessions required by the animals until reaching criterion performance. An additional group...