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R. J. Wolters

1 paper in the library · publishing 1975

Papers

ChemInform Abstract: CONFORMATIONALLY CONSTRAINED ANALOGS OF MESCALINE

Chemischer Informationsdienst January 14, 1975 R. J. Wolters, A. J. Bej, N. S. Tanner

A chemical reaction converts 3,4,5-trimethoxyphenylacetonitrile (I) with bromopropionitrile in the presence of sodium hydride in dimethylformamide to yield a glutaronitrile derivative (II) in 50% yield. Subsequent alkaline hydrolysis of (II) produces a glutaric acid derivative (III) in 77% yield.