Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al.
Molecular Psychiatry February 17, 2022 Guang Chen, G. Mannens, Marlies de Boeck et al. 14 citations
antidepressant ef fi cacy without dissociative effects ” . Open-label study results cannot be used to establish ef fi cacy, partly because they increase the expectancy biases of both the rater and the patient, and even patients with treatment-resistant depression have shown large placebo effect sizes in trials involving various treatment modalities [17]. Thus, as indicated by Bonaventura et al.,...