Features of Dissociation Differentially Predict Antidepressant Response to Ketamine in Treatment-Resistant Depression
Journal of Affective Disorders February 17, 2018 Mark J. Niciu, Bridget J. Shovestul, Brittany A. Jaso et al. 134 citations
Background Ketamine induces rapid and robust antidepressant effects, and many patients also describe dissociation, which is associated with antidepressant response. This follow-up study investigated whether antidepressant efficacy is uniquely related to dissociative symptom clusters. Methods Treatment-resistant patients with major depressive disorder (MDD) or bipolar disorder (BD) (n=126) drawn...