Raja Suhail Shounthoo

Ketamine renaissance: Expanding horizons from anesthesia to depression and pain

Asian Journal of Medical Sciences June 30, 2026 Raja Suhail Shounthoo, Ajaiz Rasool, Athar Un Nisa Quraishi et al.

Ketamine, a dissociative anesthetic introduced in the 1960s, has re-emerged as a versatile therapeutic agent extending beyond its traditional perioperative role. Its rapid antidepressant action in treatment-resistant depression and efficacy in acute and chronic pain syndromes have driven what is termed the “ketamine renaissance.” Unlike conventional monoaminergic antidepressants, ketamine...