Serial Ketamine Infusions as Adjunctive Therapy to Inpatient Care for Depression
JAMA Psychiatry October 22, 2025 A. Jelovac, Cathal Mccaffrey, Masashi Terao et al. 13 citations
Key Points Question For inpatients with moderate to severe depression, is repeated intravenous ketamine superior to a psychoactive placebo (midazolam) in reducing depressive symptoms? Findings In this randomized clinical trial, there was no statistically significant difference in the primary outcome, end-of-treatment Montgomery-Åsberg Depression Rating Scale score, between the ketamine and...