Th17 Cells in Depression: Are They Crucial for the Antidepressant Effect of Ketamine?
Frontiers in Pharmacology April 15, 2021 Meiying Cui, Wanlin Dai, Jing Kong et al. 43 citations
Background: Major depressive disorder is associated with inflammation and immune processes. Depressive symptoms correlate with inflammatory markers and alterations in the immune system including cytokine levels and immune cell function. Th17 cells are a T cell subset which exerts proinflammatory effects. Th17 cell accumulation and Th17/Treg imbalances have been reported to be critical in the...