Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder.
Cochrane Database of Systematic Reviews September 12, 2021 Rebecca L. Dean, Claudia C. Hurducas, Keith Hawton et al. 97 citations
BACKGROUND Many studies have recently been conducted to assess the antidepressant efficacy of glutamate modification in mood disorders. This is an update of a review first published in 2015 focusing on the use of glutamate receptor modulators in unipolar depression. OBJECTIVES To assess the effects - and review the acceptability and tolerability - of ketamine and other glutamate receptor...