Depression and antidepressant effects of ketamine and its metabolites: The pivotal role of gut microbiota.
Neuropharmacology September 1, 2022 Hao-Ming Hua, Chao Huang, Hanyu Liu et al. 35 citations
The discovery of the robust antidepressant actions of ketamine is regarded as one of the greatest advancements in depression treatment in the past 60 years. Recent findings have provided strong evidence for the presence of bidirectional communication networks between the gastrointestinal tract and the brain in depression. Moreover, increasing evidence supports the antidepressant role of...