BACKGROUND Ketamine is established as a rapid and effective treatment in adults with treatment-resistant depression (TRD). The availability of different formulations and routes of delivery invites the need for evaluating relative effect sizes. METHODS Effect size with respect to depression symptom reduction for each formulation and route of delivery was compared at discrete time-points (i.e.,...
Alasdair Coles is an academic neurologist in Cambridge, mainly working on experimental therapies in multiple sclerosis. He is also an Anglican priest. Funded by the Templeton Foundation, he has led two studies of the effect of neurological diseases on spirituality: Parkinson’s disease and temporal lobe epilepsy. He has edited ‘Neurology and Religion’, to be published by CUP in 2019. Since...