Real-world effectiveness of ketamine in treatment-resistant depression: A systematic review & meta-analysis.
Journal of Psychiatric Research May 1, 2022 Yazen Alnefeesi, David C J Chen-Li, Ella Krane et al. 177 citations
Ketamine is a promising therapeutic option in treatment-resistant depression (TRD). The acute efficacy of ketamine in TRD has been demonstrated in replicated randomised-controlled trials (RCTs), but the generalizability of RCT data to real-world practice is limited. To this end, we conducted a systematic review (Search date: 25/12/2021; 1482 records identified) and meta-analysis of studies...