Acute cannabidiol (CBD), tetrahydrocannabinol (THC) and their mixture (THC:CBD) exert differential effects on brain activity and blood flow in rats: A translational neuroimaging study.
Journal of Psychopharmacology March 1, 2026 Eilidh Macnicol, Michelle Kokkinou, Maria Elisa Serrano Navacerrada et al. 2 citations
Cannabis constituents, including Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), show distinct pharmacological profiles with therapeutic relevance for neurological and psychiatric conditions. THC exerts euphoric effects primarily via CB1 receptor activation, while CBD displays non-euphoric properties affecting various pathways. This study evaluated the effects of THC, CBD, and their...
DOI: 10.1177/02698811251360745 (opens in new tab)
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Cannabinoids
Cerebral blood flow
Neuroimaging
Rat
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