Pharmacological therapies for early and long-term recovery in disorders of consciousness: current knowledge and promising avenues.
Expert Review of Neurotherapeutics June 1, 2025 Rosalie Girard Pepin, Fatemeh Seyfzadeh, David Williamson et al. 7 citations
Disorders of consciousness (DoC) are characterized by impaired arousal and/or awareness, ranging from coma to unresponsive wakefulness syndrome, minimally conscious state, and cognitive motor dissociation. Pharmacological treatment options remain limited, complicated by the heterogeneity of etiologies, such as traumatic brain injury, stroke, and infections. The lack of rigorous clinical trials...