Ketamine's Therapeutic Role in Substance Use Disorders: A Narrative Review.
NeuroSci August 27, 2025 Alexander Thomas, R Andrew Chambers 4 citations
Interest in ketamine as a novel treatment for substance use disorders (SUDs) has been increasing due to its N-methyl-D-aspartate (NMDA) glutamate receptor antagonism and mounting evidence that glutamate neurotransmission is involved in the pathogenesis of both depression and addictions. This narrative review provides an outline of clinical evidence reported in the literature from the 1970s to...
DOI: 10.3390/neurosci6030083 (opens in new tab)
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Ketamine
Nmda n-methyl-d-aspartate
Case reports
Cohort studies
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