THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid.
Journal of Psychoactive Drugs January 1, 2024 Daniel J. Kruger, Carlton Cb Bone, Meredith C Meacham et al. 9 citations
A survey of THC-O-acetate users found that the semi-synthetic cannabinoid produces low to moderate cognitive distortions—altered sense of time, concentration difficulties, and short-term memory problems—with few visuals or hallucinations. Scores on the Mystical Experience Questionnaire were significantly below the threshold for a complete mystical experience across all four dimensions. Users who had previously used classic psychedelics (5-HT2A agonists) scored lower on all dimensions. When asked directly, 79% of respondents said using THC-O-acetate is "not at all" or "a little" of a psychedelic experience. Some reports of psychedelic effects may stem from expectations or contaminants.