Concurrent assessment of neurometabolism and brain hemodynamics to characterize the functional brain response to psychotropic drugs: An S-ketamine study.
Journal of Cerebral Blood Flow & Metabolism April 1, 2026 Daphne E Boucherie, Liesbeth Reneman, Jan Booij et al.
Neuroimaging techniques offer valuable insights for understanding pharmacological treatment effects in neuropsychiatric disorders. Here, we present a novel approach that simultaneously assesses hemodynamic and neurometabolic brain responses to psychotropic drugs using interleaved pharmacological magnetic resonance imaging (phMRI) and pharmacological magnetic resonance spectroscopy (phMRS). This...
DOI: 10.1177/0271678x251399023 (opens in new tab)
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S-ketamine
Dissociation
Functional mrs
Pharmacological MRI
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