Daphne E Boucherie

2 papers in the library · publishing 2023-2026

Papers

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Concurrent assessment of neurometabolism and brain hemodynamics to characterize the functional brain response to psychotropic drugs: An S-ketamine study.

Journal of Cerebral Blood Flow & Metabolism April 1, 2026 Daphne E Boucherie, Liesbeth Reneman, Jan Booij et al.

Neuroimaging techniques offer valuable insights for understanding pharmacological treatment effects in neuropsychiatric disorders. Here, we present a novel approach that simultaneously assesses hemodynamic and neurometabolic brain responses to psychotropic drugs using interleaved pharmacological magnetic resonance imaging (phMRI) and pharmacological magnetic resonance spectroscopy (phMRS). This...

DOI: 10.1177/0271678x251399023 Full text S-ketamine Dissociation Functional mrs Pharmacological MRI +1

Neurometabolite changes in response to antidepressant medication: A systematic review of 1H-MRS findings.

NeuroImage: Clinical 2023 Daphne E Boucherie, Liesbeth Reneman, Henricus G. Ruhé et al.

Selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and (es)ketamine are used to treat major depressive disorder (MDD). These different types of medication may involve common neural pathways related to glutamatergic and GABAergic neurotransmitter systems, both of which have been implicated in MDD pathology. We conducted a systematic review...

DOI: 10.1016/j.nicl.2023.103517 Full text Esketamine Major depressive disorder 1h-mrs Gaba +3