International Journal of Drug Policy
July 1, 2026
Salim Mezaache, Liselotte Pochard, Hélène Peyrière et al.
Ketamine analogues are emerging dissociative substances structurally related to ketamine and increasingly detected on drug markets worldwide. This study aimed to characterize patterns of use, user profiles, and associated health outcomes in France. We conducted a retrospective analysis of cases involving ketamine analogues reported to the French Addictovigilance Network up to 31 December 2024....
Journal of Psychopharmacology
February 23, 2026
Tiphaine Raingeard, Thomas Soeiro, Caroline Victorri-Vigneau et al.
Background: While ketamine is widely used in anesthesia and pain management, its non-medical use is increasing worldwide. In France, surveillance data indicate a sharp rise in ketamine-related disorders, but comprehensive characterization of affected patients and associated complications remains limited. Aims: To examine trends on ketamine in France from 2019 to 2023, and describe severe...
Fundamental and Clinical Pharmacology
June 2022
Jules Baudot, Thomas Soeiro, Marine Tambon et al.
Prominent features of esketamine (e.g., similar mechanism of action as ketamine and target population) require to be vigilant regarding its benefits/risks balance and its risks of abuse in real-life settings. The aim of this study was to review all available pharmacological and clinical data to assess the abuse potential of esketamine shortly after its marketing. This multidimensional study is...
The´rapie
2022
Joëlle Micallef, Anne Batisse, Bruno Revol
Scientific knowledge about cannabidiol (CBD) demonstrates that CBD is a substance that is not pharmacologically inert. If it does not act efficiently on cannabinoid receptors (those where tetrahydrocannabidol [THC] is fixed), it acts on brain receptors, especially on dopamine and serotonin receptors, making it a psychoactive product in its own right. Its consumption can thus have psychoactive...
Fundamental and Clinical Pharmacology
May 12, 2018
Joëlle Micallef, Julien Dupouey, Élisabeth Jouve et al.
59 citations
Driving experiments in real conditions are considered as a 'gold standard' to evaluate the effects of drugs on driving performance. Several constraints are difficult to manage in these conditions, so driving simulation appears as the best alternative. A preliminary comparison is crucial before being able to use driving simulation as a valid evaluation method. The aim of this study was to design...