Ketamine Psychedelic and Antinociceptive Effects Are Connected
Anesthesiology February 21, 2022 Erik Olofsen, Jasper Kamp, Thomas K. Henthorn et al. 33 citations
BACKGROUND: Ketamine produces potent analgesia combined with psychedelic effects. It has been suggested that these two effects are associated and possibly that analgesia is generated by ketamine-induced dissociation. The authors performed a post hoc analysis of previously published data to quantify the pharmacodynamic properties of ketamine-induced antinociception and psychedelic symptoms. The...