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Leo J. Schep

3 papers in the library · 93 citations · publishing 2016-2023

Papers

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The clinical toxicology of ketamine

Clinical Toxicology June 2, 2023 Leo J. Schep, Robin J Slaughter, Martin Watts et al. 63 citations

INTRODUCTION: Ketamine is a pharmaceutical drug possessing both analgesic and anaesthetic properties. As an anaesthetic, it induces anaesthesia by producing analgesia with a state of altered consciousness while maintaining airway tone, respiratory drive, and hemodynamic stability. At lower doses, it has psychoactive properties and has gained popularity as a recreational drug. OBJECTIVES: To...

Ibogaine for treating drug dependence. What is a safe dose?

Drug and Alcohol Dependence September 1, 2016 Leo J. Schep, Robin J Slaughter, S Galea et al. 30 citations

The indole alkaloid ibogaine, present in the root bark of the West African rain forest shrub Tabernanthe iboga, has been adopted in the West as a treatment for drug dependence. Treatment of patients requires large doses of the alkaloid to cause hallucinations, an alleged integral part of the patient's treatment regime. However, case reports and case series continue to describe evidences of...

Case series: toxicity from 25B-NBOMe--a cluster of N-bomb cases.

Clinical toxicology (Philadelphia, Pa.) 2016 Paul Gee, Leo J. Schep, Berit P Jensen et al.

Background A new class of hallucinogens called NBOMes has emerged. This class includes analogues 25I-NBOMe, 25C-NBOMe and 25B-NBOMe. Case reports and judicial seizures indicate that 25I-NBOMe and 25C-NBOMe are more prevalently abused. There have been a few confirmed reports of 25B-NBOMe use or toxicity. Report Observational case series. This report describes a series of 10 patients who suffered...