Repurposing potential of ketamine: Opportunities and challenges
Indian Journal of Psychological Medicine January 17, 2020 C S Gautam, Sonia S Mahajan, Jatin Sharma et al. 31 citations
Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor which also interacts with various other receptors that account for its myriad actions. Originally approved as a general anesthetic, it is being explored to be repurposed for numerous other indications such as depressive disorders, suicidal ideation, substance-use disorders, anxiety disorders, chronic pain,...