Modulation of inhibitory control networks relate to clinical response following ketamine therapy in major depression.
Translational Psychiatry July 30, 2020 Ashish K Sahib, Joana Ra Loureiro, Megha M Vasavada et al. 37 citations
Subanesthetic ketamine is found to induce fast-acting and pronounced antidepressant effects, even in treatment resistant depression (TRD). However, it remains unclear how ketamine modulates neural function at the brain systems-level to regulate emotion and behavior. Here, we examined treatment-related changes in the inhibitory control network after single and repeated ketamine therapy in TRD....