Modulation of the functional connectome in major depressive disorder by ketamine therapy.
Psychological Medicine October 1, 2022 Ashish K Sahib, Joana R Loureiro, Megha M Vasavada et al. 36 citations
Subanesthetic ketamine infusion therapy can produce fast-acting antidepressant effects in patients with major depression. How single and repeated ketamine treatment modulates the whole-brain functional connectome to affect clinical outcomes remains uncharacterized. Data-driven whole brain functional connectivity (FC) analysis was used to identify the functional connections modified by ketamine...
DOI: 10.1017/s0033291720004560 (opens in new tab)
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Ketamine
Functional connectivity
Major depression
Salience network