Therapeutic potential of ketamine for alcohol use disorder.
Neuroscience and Biobehavioral Reviews July 1, 2021 Stephen D Worrell, Thomas J Gould 47 citations
Excessive alcohol consumption is involved in 1/10 of deaths of U.S. working-age adults and costs the country around $250,000,000 yearly. While Alcohol Use Disorder (AUD) pathology is complex and involves multiple neurotransmitter systems, changes in synaptic plasticity, hippocampal neurogenesis, and neural connectivity have been implicated in the behavioral characteristics of AUD. Depressed...