Beyond Anesthesia: Ketamine’s Expanding Role in Chronic Pain and Psychiatric Disorders
Journal of Integrative Neuroscience July 25, 2025 Christopher Zaki 1 citation
OBJECTIVE: This review explores ketamine's expanding role in managing both chronic pain and mental health conditions, focusing on its pharmacologic mechanisms, clinical applications, and therapeutic potential. We assess its analgesic properties, FDA-approved application in the form of Spravato (esketamine) for depression, and off-label use for analgesia and psychiatric disorders. METHODS: A...