Beyond the High: A Narrative Review of the Chronic Complications of Recreational Ketamine Use.
British journal of hospital medicine (London, England : 2005) May 18, 2026 Karen L Erskine, Paul I Dargan, David M Wood
Ketamine, initially developed as a dissociative anaesthetic, has seen expanding therapeutic applications, in managing treatment-resistant depression and chronic pain. However, its psychoactive properties have also been associated with a significant rise in recreational use globally. Chronic, high-dose recreational ketamine use is associated with dependence potential and a spectrum of long-term...