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Jennifer B. Dwyer

2 papers in the library · 66 citations · publishing 2022-2024

Papers

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Exploring Predictors of Ketamine Response in Adolescent Treatment-Resistant Depression

Journal of Child and Adolescent Psychopharmacology January 3, 2024 Alice Lineham, Victor J. Avila‐quintero, Michael H. Bloch et al. 15 citations

Objective:Ketamine has proved effective as a rapid-acting antidepressant agent, but treatment is not effective for everyone (approximately a quarter to a half of patients). Some adult studies have begun to investigate predictors of ketamine's antidepressant response, but no studies have examined this in adolescents with depression. Methods:We conducted a secondary data analysis of adolescents...

Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression: A Randomized Midazolam-Controlled Trial

FOCUS The Journal of Lifelong Learning in Psychiatry April 1, 2022 Jennifer B. Dwyer, Angeli Landeros‐Weisenberger, Jessica A. Johnson et al. 51 citations

Objective: Adolescent depression is prevalent and is associated with significant morbidity and mortality. Although intravenous ketamine has shown efficacy in adult treatment-resistant depression, its efficacy in pediatric populations is unknown. The authors conducted an active-placebo-controlled study of ketamine's safety and efficacy in adolescents. Methods: In this proof-of-concept...