Neuroimage. Reports
June 1, 2026
Sarah Rempel, Maria McDonald, Veit Roessner et al.
Cognitive flexibility is a core executive function often impaired in individuals with obsessive-compulsive disorder (OCD). Mindfulness-based interventions have been hypothesized to improve cognitive flexibility and may be a promising adjunctive intervention for adolescents with OCD. The current study examines which cognitive neurophysiological processes underlie mindfulness-based interventions...
Journal of Clinical Medicine
March 24, 2023
Sarah Rempel, Lea L. Backhausen, Maria McDonald et al.
(1) Background: 1–2% of children and adolescents are affected by Obsessive-Compulsive Disorder (OCD). The rigid, repetitive features of OCD and an assumed disability to inhibit recent mental representations are assumed to have led to a paradoxical advantage in that the Backward Inhibition (BI) effect was recently found to be lower in adolescents with OCD as compared to healthy controls. It was...
Addiction Science & Clinical Practice
September 4, 2022
Lukas Andreas Basedow, Melina Felicitas Wiedmann, Veit Roessner et al.
17 citations
Abstract Background Post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) often co-occur in adolescent patients. Previous research has shown that these patients differ from SUD patients without PTSD in terms of their substance use patterns. In this study, we aimed to test whether substance use in this population is related to an attempt to self-medicate PTSD-related symptoms....
Frontiers in Psychiatry
January 21, 2022
Melina Wiedmann, Sören Kuitunen-Paul, Lukas A Basedow et al.
5 citations
ObjectivesBoth substance use, on the one hand, and the first signs of psychosis, on the other, commonly begin in adolescence. Adolescents with substance use disorder (SUD) frequently show recreational use of cannabis and 3,4-methylenedioxymethamphetamine (MDMA). When attenuated psychotic symptoms (APS) occur during the course of SUD, they are commonly attributed to the cannabis use, neglecting...
European Journal of Psychotraumatology
2021
Lukas A Basedow, Sören Kuitunen-Paul, Melina Wiedmann et al.
15 citations
ABSTRACT Background: Adolescent patients with a substance use disorder (SUD) often fulfil the criteria for a co-occurring post-traumatic stress disorder (PTSD). However, it is not clear if these dual-diagnosed adolescents present with unique levels of substance use and how their substance use relates to PTSD symptom clusters. Objective: To investigate substance use in adolescents with...