bioRxiv Preprint ServerJanuary 14, 2026Muad Y. Abd El Hay, Ana Cukić, Marieke Schölvinck et al.
preprint
Psychedelic substances show promise for treating psychiatric disorders including depression, anxiety, and PTSD, but the neurobiological mechanisms underlying their therapeutic effects remain poorly understood. Preclinical findings have so far been inconsistent, limiting mechanistic insights. We argue this translational gap is exacerbated by systematic disconnects between conditions thought to...