Patients with arginine vasopressin (AVP) deficiency (formerly central diabetes insipidus) often report social and emotional deficits and heightened anxiety. Growing evidence suggests that these symptoms may, at least partly, reflect concomitant OXT deficiency. OXT plays a key role in increasing empathy and improving emotion recognition. This analysis aimed to examine empathy and emotion...
Oxytocin (OXT) deficiency is a recently identified novel psycho-neuroendocrine entity associated with anxiety and reduced prosocial behavior. However, diagnosis and clinical progress have been hindered by challenges in reliably measuring OXT. Neurophysin I (NP-I), an equimolarly co-released cleavage product of the OXT precursor peptide, offers a promising alternative biomarker due to its...