Therapeutic effects of psilocybin in major depressive disorder: a systematic review and meta-analysis exploring dose effects.
European Archives of Psychiatry and Clinical Neuroscience June 1, 2026 Ziping He, Yijie Wang, Jiemin Chen et al. 1 citation
BACKGROUND: Several recent trials indicate positive effects of psilocybin in patients with major depressive disorder. However, questions need to be addressed regarding the relationship between dosage and therapeutic outcomes, such as the recommended dose range and frequency for optimal practice as well as the dose-dependent adverse effects. OBJECTIVE: (1) to assess the effectiveness and...